drugset / Trial / NCT00629889
Levetiracetam or Pregabalin in Treating Seizures in Patients Undergoing Chemotherapy and/or Radiation Therapy For Primary Brain Tumors
RandomizedParallel-groupOpen-labelSupportive care
Summary
RATIONALE: Levetiracetam and pregabalin are drugs that treat seizures. It is not yet known which drug is more effective in treating seizures caused by primary brain tumors. PURPOSE: This randomized phase II trial is studying the side effects and how well levetiracetam or pregabalin work in treating seizures in patients undergoing chemotherapy and/or radiation therapy for primary brain tumors.
Timeline
- Start
- 2008-02
- Primary completion
- 2012-05
- Completion
- 2013-05
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Levetiracetam | Other / unclassified | 1500 mg | — |
| Comparator | Pregabalin | Small molecule | 300 mg | — |