Efficacy and Safety of Celecoxib Versus Ibuprofen in the Treatment of Osteoarthritis of the Knee (Europe)

Summary

To compare the efficacy and safety of celecoxib versus ibuprofen in subjects with osteoarthritis (OA) of the knee.

Timeline

Start

2003-01

Primary completion

—

Completion

2004-02

Outcome

Met primary endpoint

paper As the lower bound was greater than -10, celecoxib was non-inferior to ibuprofen. PMID 28222627 ↗

Publications

• Gordo AC, Walker C, Armada B, Zhou D. Efficacy of celecoxib versus ibuprofen for the treatment of patients with osteoarthritis of the knee: A randomized double-blind, non-inferiority trial. J Int Med Res. 2017 Feb;45(1):59-74. doi: 10.1177/0300060516673707. Epub 2017 Jan 12.

Drugs

Indications