High Dose Methotrexate With Leucovorin Rescue With or Without Glucarpidase in Osteosarcoma

Summary

The purpose of this study is to demonstrate whether use of glucarpidase facilitates administration of the next cycle of chemotherapy as scheduled and improves safety and tolerability of HDMTX given with LV

Timeline

Start

2008-10

Primary completion

2009-03

Completion

2009-04

Drugs

Indications