Treatment of Acne Vulgaris With Doryx Tablets Compared to Doxycyline Hyclate
Summary
Randomized, multi-center, open label, active-comparator study to compare the efficacy and tolerability of Doryx Delayed Release Tablets to doxycycline hyclate in patients with moderate to severe acne vulgaris.
Timeline
- Start
- 2008-03
- Primary completion
- 2008-09
- Completion
- 2008-09
Outcome
Mixed primary results
registry Doxycycline Hyclate (Doryx) Delayed-release Tablets vs Doxycycline Hyclate Immediate-release Tablets; p = 0.765; Cochran-Mantel-Haenszel NCT00635609 ↗
registry MEAN Doxycycline Hyclate (Doryx) Delayed-release Tablets: 21.8 (Standard Deviation 13.8) acne lesion count NCT00635609 ↗
registry MEAN Doxycycline Hyclate Immediate-release Tablets: 26.6 (Standard Deviation 12.5) acne lesion count NCT00635609 ↗
registry Doxycycline Hyclate (Doryx) Delayed-release Tablets vs Doxycycline Hyclate Immediate-release Tablets; p = 0.033; Cochran-Mantel-Haenszel NCT00635609 ↗
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Doxycycline | Small molecule | 100 mg | Oral |
| Subject | Doxycycline | Small molecule | 150 mg | Oral |