drugset / Trial / NCT00636246
A Comparison of Sertraline-reboxetine Combination Therapy Versus Sertraline or Reboxetine Monotherapy in the Treatment of Major Depression.
RandomizedParallel-groupDouble-blindTreatment
Summary
This study was designed to determine if the novel combination of the SSRI, sertraline, and the NRI reboxetine will increase antidepressant efficacy without sacrificing the favorable safety profile of SSRIs.
Timeline
- Start
- 2004-06
- Primary completion
- —
- Completion
- 2005-08
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Sertraline | Small molecule | 150 mg | Oral |
| Subject | [S,S]-Reboxetine | Unknown | 2 mg | Oral |
| Subject | [S,S]-Reboxetine | Unknown | 4 mg | Oral |
| Subject | [S,S]-Reboxetine | Unknown | 6 mg | Oral |