drugset / Trial / NCT00639366

Radiation Therapy to the Head in Preventing Brain Metastases in Women Receiving Trastuzumab and Chemotherapy for Metastatic or Locally Advanced Breast Cancer

NCT00639366

Phase 3 Completed 390 enrolled Anglo Celtic Cooperative Oncology Group
RandomizedPrevention

Summary

RATIONALE: Radiation therapy uses high-energy x-rays to kill tumor cells. It is not yet known whether radiation therapy directed at the head is effective in preventing brain metastases in patients with advanced cancer. PURPOSE: This randomized phase III trial is studying radiation therapy to the head to see how well it works in preventing brain metastases in women receiving trastuzumab and chemotherapy for metastatic or locally advanced breast cancer.

Timeline

Start
2007-02
Primary completion
2010-02
Completion
2010-10

Drugs

EvaluationDrugModalityDoseRoute
Background Trastuzumab Monoclonal antibody

Indications