drugset / Trial / NCT00643292

A Single, High-Dose Azithromycin Extended Release (60 mg/kg) Compared With 10 Days of High-Dose Amoxicillin Clavulanate in Children With Ear Infections at High Risk of Persistent/Recurrent Ear Infections

NCT00643292

Phase 3 Completed 902 enrolled Pfizer
RandomizedParallel-groupDouble-blindTreatment

Summary

A phase 3 randomized, multicenter, double blind, double dummy study to assess the efficacy, safety, and compliance of a single dose of azithromycin extended release compared with a 10-day course of amoxicillin/clavulanate twice daily in children at high risk for persistent or recurrent ear infections

Timeline

Start
2003-01
Primary completion
Completion
2004-05

Drugs

EvaluationDrugModalityDoseRoute
Subject Amoxicillin Other / unclassified 90 mg/kg
Subject Azithromycin Small molecule 60 mg/kg
Subject Clavulanate Unknown 6.4 mg/kg

Indications