Prolonged Adjuvant Temozolomide vs "Stop & Go" in Glioblastoma Patients

Summary

This study will test the hypothesis that prolonged adjuvant Temozolomide (TMZ) may delay relapses in patients with glioblastoma compared to the standard care consisting in observation with brain MRI every 3 months and rechallenging with TMZ at relapse (Stop and Go arm).

Timeline

Start

2008-01

Primary completion

2011-01

Completion

2012-01

Drugs

Indications