drugset / Trial / NCT00644553
Comparative Study of the Safety and Efficacy of Clarithromycin Extended-Release Tablets Versus Amoxicillin-Clavulanate for the Treatment of Acute Bacterial Sinusitis
RandomizedParallel-groupSingle-blindTreatment
Summary
To compare the safety/tolerability and efficacy of a 14-day course of clarithromycin extended-release tablets (2 x 500 mg QD) with that of a 14-day course of amoxicillin-clavulanate tablets (875/125 mg BID) for the treatment of ambulatory subjects with Acute Bacterial Sinusitis (ABS).
Timeline
- Start
- 2003-05
- Primary completion
- 2004-03
- Completion
- —
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Amoxicillin | Other / unclassified | 875 mg | Oral |
| Comparator | Clarithromycin | Small molecule | 1000 mg | Oral |
| Subject | Clavulanate | Unknown | 125 mg | Oral |