LXRA Gene Polymorphisms and Response to Fenofibrate

Terminated 11 enrolled University of Florida American College of Clinical Pharmacy · collab

RandomizedCrossoverQuadruple-blindBasic science

Summary

This is a research study of how a cholesterol medication known as fenofibrate works differently in people with different genetic backgrounds. "Genetics" refers to certain things that are passed to a person by their parents, such as eye color or hair color. Genetic differences lead to people having different eye and hair color. There are also genetic differences in a protein called liver X receptor-alpha (LXRA), which may be important in predicting the response to fenofibrate.

Timeline

Start: 2008-03
Primary completion: 2009-08
Completion: 2009-08

Drugs

Evaluation	Drug	Modality	Dose	Route
Comparator	Fenofibrate	Small molecule	160 mg	Oral

Indications

No indication recorded.