drugset / Trial / NCT00650910
Study To Examine The Effects Of Lapatinib On The Pharmacokinetics Of Digoxin In Subjects w/ ErbB2 Positive Breast Cancer
NaSingle-groupOpen-labelTreatment
Summary
This is a two part study looking at the effect of lapatinib on concentrations of digoxin in the blood when both drugs are dosed together in Part 1; and looking at the safety and antitumor effect of lapatinib when used together with possible additional anticancer therapy as chosen at the doctor's discretion.
Timeline
- Start
- 2008-04-23
- Primary completion
- 2009-07-10
- Completion
- 2009-07-10
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Digoxin | Other / unclassified | 0.5 mg | Oral |
| Subject | Lapatinib | Small molecule | 1500 mg | Oral |