drugset / Trial / NCT00656357
Study of Safety and Potential Efficacy of SYN117 in Cocaine Dependent Volunteers
Phase 1/2
Completed
20 enrolled
Biotie Therapies Inc.
National Institute on Drug Abuse (NIDA) · collab
RandomizedParallel-groupTriple-blindTreatment
Summary
This study will assess the potential interaction and subjective effects between intravenous cocaine and SYN117 in non-treatment seeking cocaine dependant subjects
Timeline
- Start
- 2008-06
- Primary completion
- 2009-05
- Completion
- 2009-05
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Cocaine | Small molecule | 10 mg | Intravenous |
| Subject | Cocaine | Small molecule | 20 mg | Intravenous |
| Subject | Cocaine | Small molecule | 40 mg | Intravenous |
| Subject | Nepicastat | Small molecule | 80 mg | — |
| Subject | Nepicastat | Small molecule | 160 mg | — |