Inhaled Corticosteroids on Airway Smooth Muscle in Asthma

Summary

The main objective is to evaluate how treatment with inhaled corticosteroids (ICS) affects the characteristics of airway smooth muscle (ASM) cells from asthmatic subjects. Our hypothesis is that airway smooth muscle cell dysfunction plays an important role in the pathogenesis of asthma, and that treatment with inhaled corticosteroids reverses the abnormalities in airway smooth muscle cell function.

Timeline

Start

2008-04

Primary completion

2010-12

Completion

2011-03

Drugs

Indications