drugset / Trial / NCT00662896

To Assess the Effect of Naproxcinod Versus Naproxen and Ibuprofen on Arterial Blood Pressure in Osteoarthritis Patients With Controlled Essential Hypertension

NCT00662896

Phase 1 Completed 300 enrolled NicOx
RandomizedParallel-groupDouble-blindTreatment

Summary

To assess the effect of naproxcinod vs. naproxen and ibuprofen on arterial blood pressure in patients with osteoarthritis and controlled essential hypertension

Timeline

Start
2008-03
Primary completion
2008-09
Completion
2008-12

Drugs

EvaluationDrugModalityDoseRoute
Comparator Ibuprofen Small molecule 600 mg
Comparator Naproxen Small molecule 250 mg
Comparator Naproxen Small molecule 500 mg
Subject naproxcinod Other / unclassified 375 mg
Subject naproxcinod Other / unclassified 750 mg