drugset / Trial / NCT00663195
Effects of Spironolactone on Matrix Metalloproteinases (MMPs) in Heart Failure
RandomizedCrossoverDouble-blindTreatment
Summary
The purpose of this study is to evaluate the effects of spironolactone on circulating MMP levels and insulin resistance in patients with chronic heart failure.
Timeline
- Start
- 2004-01
- Primary completion
- —
- Completion
- 2005-12
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Spironolactone | Small molecule | 25 mg | — |
| Background | Furosemide | Other / unclassified | 20 mg | — |