Bronchial Hyper-responsiveness in Reflux Cough

Phase 3 Terminated 5 enrolled Hull University Teaching Hospitals NHS Trust

NaSingle-groupOpen-labelHealth-services research

Summary

The study aim is to determine the effect of 8 weeks of anti-reflux treatment (full acid suppression) on bronchial hyper-responsiveness and whether there is a symptomatic improvement.

Timeline

Start: 2006-09
Primary completion: 2009-09
Completion: 2010-01

Publications

Background Morice AH, Kastelik JA, Thompson R. Cough challenge in the assessment of cough reflex. Br J Clin Pharmacol. 2001 Oct;52(4):365-75. doi: 10.1046/j.0306-5251.2001.01475.x. No abstract available.

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	Omeprazole	Other / unclassified	20 mg	Oral
Subject	Ranitidine	Unknown	300 mg	Oral

Indications

No indication recorded.