drugset / Trial / NCT00668824

Improved Diagnosis of Congenital Heart Disease by Magnetic Resonance Imaging Using Vasovist

NCT00668824

Phase 4 Unknown Guy's Hospital
Diagnostic

Summary

Magnetic Resonance Imaging (MRI) is an effective and radiation free method of diagnosing Congenital Heart Disease (CHD). MRI works by taking images of the anatomy and physiology. These images also provide information on the hearts function and blood flow. The clarity of these images is enhanced by the use of contrast agents (dyes). However these agents only stay in the blood vessels for a short time and therefore limit the time in which the better quality images can be obtained. This study aims to determine whether MRI using Vasovist (a dye that stays in the vessels for a prolonged period of time) can improve the diagnosis of Congenital Heart Disease (CHD) by allowing more areas to be imaged and the improved assessment of various parameters (anatomy, volumes, flow) as well as vastly improving image quality.

Timeline

Start
2007-03
Primary completion
2008-07
Completion
2009-12

Drugs

EvaluationDrugModalityDoseRoute
Subject Vasovist Diagnostic / imaging agent