drugset / Trial / NCT00671216
A Study to Assess the Safety and Pharmacokinetics of Inhaled Doses of GSK233705 and GW642444 in Healthy Subjects.
RandomizedCrossoverDouble-blindTreatment
Summary
GW642444 and GSK233705 are in development for treatment of Chronic Obstructive Pulmonary Disease. Development of these two inhaled drugs as a combination therapy would have potential for improved patient benefit as they both work through different mechanisms and the combined bronchodilatory effect might be additive. This study will look at the this combination, for the first time, in healthy subjects.
Timeline
- Start
- 2008-05-20
- Primary completion
- 2008-07-07
- Completion
- 2008-07-07
Publications
- Background GSK has concluded that it is not feasible to publish this study in a peer-reviewed scientific journal because the nature of the study is unlikely to be of interest to a journal. GSK is providing the attached study results summary.
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | DAROTROPIUM | Small molecule | 200 ug | Inhaled |
| Subject | Vilanterol | Other / unclassified | 50 ug | Inhaled |