Food Effects of Single Oral Dose of 600mg TR-701

Phase 1 Completed 12 enrolled Merck & Co., Inc.

RandomizedCrossoverOpen-labelBasic science

Summary

This is an evaluation of the safety, tolerance, and pharmacokinetics of single oral doses of TR-701 given to normal, healthy, adult volunteers in the fed and fasted state.

Timeline

Start: 2008-03-10
Primary completion: 2008-05-15
Completion: 2008-05-15

Publications

Flanagan SD, Bien PA, Munoz KA, Minassian SL, Prokocimer PG. Pharmacokinetics of tedizolid following oral administration: single and multiple dose, effect of food, and comparison of two solid forms of the prodrug. Pharmacotherapy. 2014 Mar;34(3):240-50. doi: 10.1002/phar.1337. Epub 2013 Aug 7.

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	TR-701	Small molecule	600 mg	Oral

Indications

No indication recorded.