Safety of Ramelteon in Subjects With Mild to Moderate Obstructive Sleep Apnea

Summary

The purpose of this study is to assess the safety of ramelteon, once daily (QD), in individuals with obstructive sleep apnea.

Timeline

Start

2003-07

Primary completion

2003-12

Completion

2003-12

Outcome

Missed primary endpoint

paper Apnea-hypopnea index was similar in ramelteon and placebo groups (11.4 vs 11.1, respectively; CI = -2.1, 2.6, P = 0.812). PMID 17294232 ↗

Publications

• Results Kryger M, Wang-Weigand S, Roth T. Safety of ramelteon in individuals with mild to moderate obstructive sleep apnea. Sleep Breath. 2007 Sep;11(3):159-64. doi: 10.1007/s11325-006-0096-4.

Drugs

Indications