drugset / Trial / NCT00672113

Effects of Adalat LA and Coracten on Drug Levels, Blood Pressure, and Heart Rate in Fed Patients With Hypertension

NCT00672113

Phase 4 Completed 43 enrolled Bayer
RandomizedCrossoverOpen-labelBasic science

Summary

This study compares the effect of Adalat LA to Coracten on drug levels as well as changes in blood pressure and heart rate in fed hypertensive subjects. Subjects are dosed with either Adalat or Coracten for first 2 weeks, followed by the other drug for 2 weeks, and then switched back to the original drug for one day. Blood samples, blood pressure, and heart rate are taken before and after each treatment period.

Timeline

Start
2003-12
Primary completion
Completion
2004-08

Drugs

EvaluationDrugModalityDoseRoute
Comparator Coracten Unknown 30 mg
Subject Nifedipine Other / unclassified 30 mg