drugset / Trial / NCT00672438

Heritability of Opioid Effects: A Twin Study

NCT00672438

Completed 242 enrolled Martin Angst SRI International · collab
RandomizedCrossoverDouble-blind

Summary

Proposed twin study will test to what degree inter-individual differences in pain sensitivity and amount of pain relief in response to opioid therapy are inherited or alternatively, are due to environmental factors. This knowledge is important to guide future studies trying to explain such inter-individual differences. For example, finding that differences are largely due to environmental factors would discourage genomic studies and emphasize epidemiological studies.

Timeline

Start
2008-05
Primary completion
2010-06
Completion
2010-06

Drugs

EvaluationDrugModalityDoseRoute
Subject Alfentanil Other / unclassified Intravenous

Indications

No indication recorded.