drugset / Trial / NCT00675207
Comparison of Brimonidine Purite, Dorzolamide, and Brinzolamide as Adjunctive Therapy to Prostaglandin Analogs
Phase 4
Completed
120 enrolled
Northwestern Ophthalmic Institute S.C.
Research to Prevent Blindness · collab
RandomizedParallel-groupSingle-blindTreatment
Summary
The purpose of this study is to compare the efficacy of brimonidine Purite, dorzolamide, and brinzolamide in reducing intraocular pressure when added to prostaglandin analog therapy (bimatoprost, latanoprost, or travoprost) in patients with glaucoma or ocular hypertension.
Timeline
- Start
- 2006-01
- Primary completion
- 2007-07
- Completion
- 2007-07
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Brimonidine | Small molecule | 0.15 % | Topical |
| Comparator | Brinzolamide | Small molecule | 1 % | Topical |
| Comparator | Dorzolamide | Small molecule | 2 % | Topical |