Lyrica Dose Response Study With Restless Legs Syndrome (RLS) Patients

Summary

To test the effectiveness and tolerability of Lyrica at various dose levels in RLS patients

Timeline

Start

2008-04

Primary completion

2009-01

Completion

2009-01

Outcome

Met primary endpoint

registry analysis (unspecified test); Placebo vs Pregabalin 150 mg; p = 0.0013; Mean Difference (Final Values) -8.29 (95% CI -13.31 to -3.28); Mixed Models Analysis NCT00676403 ↗

Publications

• Allen R, Chen C, Soaita A, Wohlberg C, Knapp L, Peterson BT, Garcia-Borreguero D, Miceli J. A randomized, double-blind, 6-week, dose-ranging study of pregabalin in patients with restless legs syndrome. Sleep Med. 2010 Jun;11(6):512-9. doi: 10.1016/j.sleep.2010.03.003. Epub 2010 May 13.

Drugs

Indications