drugset / Trial / NCT00677716

Dose Confirmation Study of Cotara for the Treatment of Glioblastoma Multiforme at First Relapse

NCT00677716 ↗

Phase 2 Completed 41 enrolled Peregrine Pharmaceuticals
NaSingle-groupOpen-labelTreatment

Summary

Cotara® is an experimental new treatment that links a radioactive isotope (iodine 131) to a targeted monoclonal antibody. This monoclonal antibody is designed to bind tumor cells and deliver radiation directly to the center of the tumor mass while minimizing effects on normal tissues. Cotara® thus literally destroys the tumor "from the inside out". This may be an effective treatment for glioblastoma multiforme, a malignant type of brain cancer.

Timeline

Start
2007-07
Primary completion
2011-09
Completion
2011-11

Drugs

EvaluationDrugModalityDoseRoute
Subject 131I-chTNT-1/B MAb Monoclonal antibody 2.5 unknown Other

Indications