drugset / Trial / NCT00677716
Dose Confirmation Study of Cotara for the Treatment of Glioblastoma Multiforme at First Relapse
NaSingle-groupOpen-labelTreatment
Summary
Cotara® is an experimental new treatment that links a radioactive isotope (iodine 131) to a targeted monoclonal antibody. This monoclonal antibody is designed to bind tumor cells and deliver radiation directly to the center of the tumor mass while minimizing effects on normal tissues. Cotara® thus literally destroys the tumor "from the inside out". This may be an effective treatment for glioblastoma multiforme, a malignant type of brain cancer.
Timeline
- Start
- 2007-07
- Primary completion
- 2011-09
- Completion
- 2011-11
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | 131I-chTNT-1/B MAb | Monoclonal antibody | 2.5 unknown | Other |