drugset / Trial / NCT00677833

Azithromycin Plus Chloroquine Versus Artemether-Lumefantrine For The Treatment Of Uncomplicated P. Falciparum Malaria In Children In Africa

NCT00677833

Phase 2/3 Completed 361 enrolled Pfizer
RandomizedParallel-groupOpen-labelTreatment

Summary

The primary objective is to confirm the hypothesis that azithromycin used in combination with chloroquine is non-inferior to artemether- Lumefantrine for the treatment of symptomatic, uncomplicated malaria due to P. falciparum in children in African countries.

Timeline

Start
2008-06
Primary completion
2010-09
Completion
2010-09

Drugs

EvaluationDrugModalityDoseRoute
Subject Artemether-lumefantrine Unknown
Subject Azithromycin Small molecule 30 mg/kg
Subject Chloroquine Small molecule 10 mg/kg