drugset / Trial / NCT00677924
Zalutumumab With or Without Irinotecan Chemotherapy in Cetuximab-Refractory Colorectal Cancer
RandomizedParallel-groupOpen-labelTreatment
Summary
The purpose of this trial is to determine the safety and efficacy of Zalutumumab alone or in combination with Irinotecan for the treatment of patients with Colorectal Cancer
Timeline
- Start
- 2008-04
- Primary completion
- 2009-04
- Completion
- 2009-04
Outcome
Outcome not reported
Stopped (Business): “Due to changes in portfolio review”
Publications
- Results Mano M, Hendlisz A, Machiels JP, Ehrnrooth E, Aladdin H, Van Laethem JL. Phase I trial of zalutumumab and irinotecan in metastatic colorectal cancer patients who have failed irinotecan and cetuximab based therapy. J Clin Oncol 27 2009 (suppl;abstr e15028)
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Zalutumumab | Monoclonal antibody | 8 mg/kg | — |
| Subject | Zalutumumab | Monoclonal antibody | 16 mg/kg | — |