drugset / Trial / NCT00680485
Evaluation of the Safety, Tolerability and Pharmacokinetics of Repeat Oral Doses of GSK580416
RandomizedCrossoverOpen-labelTreatment
Summary
This study will evaluate the safety, tolerability and exposure of repeat escalating oral doses, a loading dose/maintenance dose regimen of GSK580416 and when co administered with ketoconazole, a PGP/CYP3A4 inhibitor.
Timeline
- Start
- 2007-06
- Primary completion
- 2007-10
- Completion
- 2007-10
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | GSK580416 | Unknown | 250 mg | Oral |
| Subject | Ketoconazole | Small molecule | 200 mg | Oral |