drugset / Trial / NCT00681395

Study to Compare the Bioavailability of ABT-335 and Rosuvastatin From ABT-143 Relative to That From the Co-administration of ABT-335 and Rosuvastatin Calcium

NCT00681395

Phase 1 Completed 64 enrolled AstraZeneca
RandomizedCrossoverOpen-labelTreatment

Summary

To evaluate safety and compare the pharmacokinetic parameters from the fixed dose combination ABT-143 relative to that from the co-administration of the two monotherapies.

Timeline

Start
2008-05
Primary completion
2008-08
Completion

Drugs

EvaluationDrugModalityDoseRoute
Subject ABT-143 Unknown 5 mg
Subject ABT-143 Unknown 20 mg
Subject ABT-143 Unknown 45 mg
Subject ABT-143 Unknown 135 mg
Comparator ABT-335 Small molecule 45 mg
Comparator ABT-335 Small molecule 135 mg
Comparator Rosuvastatin Small molecule 5 mg
Comparator Rosuvastatin Small molecule 20 mg

Indications

No indication recorded.