A Multiple Ascending Dose Study of RO4998452 in Patients With Type 2 Diabetes Mellitus.

Summary

This study will evaluate the safety, tolerability, pharmacokinetics and pharmacodynamics of multiple ascending doses of RO4998452 compared to placebo in patients with type 2 diabetes mellitus. Successive cohorts of patients will be randomized to receive either active drug, at escalating doses, or placebo. The anticipated time on study treatment is \<3 months, and the target sample size is \<100 individuals.

Timeline

Start

2008-05

Primary completion

2009-03

Completion

2009-03

Drugs

Indications