Employment-Based Depot Naltrexone Clinical Trial II

Summary

The purpose of this study is to determine whether employment-based naltrexone treatment proves effective in promoting depot naltrexone adherence and drug abstinence.

Timeline

Start

2008-05

Primary completion

2010-04-30

Completion

2010-04-30

Outcome

Met primary endpoint

registry analysis (superiority test); Work Plus Naltrexone Prescription vs Work Plus Naltrexone Contingency; p = 0.0081; t-test, 2 sided NCT00684775 ↗

Publications

• Results DeFulio A, Everly JJ, Leoutsakos JM, Umbricht A, Fingerhood M, Bigelow GE, Silverman K. Employment-based reinforcement of adherence to an FDA approved extended release formulation of naltrexone in opioid-dependent adults: a randomized controlled trial. Drug Alcohol Depend. 2012 Jan 1;120(1-3):48-54. doi: 10.1016/j.drugalcdep.2011.06.023. Epub 2011 Jul 22.

Drugs

Indications