Safety and Tolerability Study of Rifaximin in Participants With a History of Hepatic Encephalopathy

Summary

This study will look at the safety of a drug used in participants who have had hepatic encephalopathy (HE) in the past.

Timeline

Start

2007-03-07

Primary completion

2010-12-08

Completion

2010-12-08

Publications

• Zacharias HD, Kamel F, Tan J, Kimer N, Gluud LL, Morgan MY. Rifaximin for prevention and treatment of hepatic encephalopathy in people with cirrhosis. Cochrane Database Syst Rev. 2023 Jul 19;7(7):CD011585. doi: 10.1002/14651858.CD011585.pub2.
• Mullen KD, Sanyal AJ, Bass NM, Poordad FF, Sheikh MY, Frederick RT, Bortey E, Forbes WP. Rifaximin is safe and well tolerated for long-term maintenance of remission from overt hepatic encephalopathy. Clin Gastroenterol Hepatol. 2014 Aug;12(8):1390-7.e2. doi: 10.1016/j.cgh.2013.12.021. Epub 2013 Dec 21.

Drugs

Indications