Insulin Glargine Versus Twice-Daily NPH

Phase 4 Terminated 27 enrolled Charles Drew University of Medicine and Science National Center for Research Resources (NCRR) · collab

RandomizedParallel-groupOpen-labelTreatment

Summary

To compare the efficacy and safety of once-nightly insulin glargine versus twice-daily NPH insulin in ethnic minority type 2 diabetic patients inadequately treated with once-nightly NPH insulin alone.

Timeline

Start: 2003-02
Primary completion: 2009-08
Completion: 2009-08

Publications

Semlitsch T, Engler J, Siebenhofer A, Jeitler K, Berghold A, Horvath K. (Ultra-)long-acting insulin analogues versus NPH insulin (human isophane insulin) for adults with type 2 diabetes mellitus. Cochrane Database Syst Rev. 2020 Nov 9;11(11):CD005613. doi: 10.1002/14651858.CD005613.pub4.

Drugs

Evaluation	Drug	Modality	Dose	Route
Comparator	NPH twice-daily	Protein / enzyme biologic	—	—
Subject	insulin glargine	Protein / enzyme biologic	—	—

Insulin Glargine Versus Twice-Daily NPH

Summary

Timeline

Publications

Drugs

Indications