drugset / Trial / NCT00688714

Study to Investigate Safety and Tolerability of a Single Dose of AZD6482

NCT00688714

Phase 1 Completed 49 enrolled AstraZeneca
RandomizedParallel-groupQuadruple-blindBasic science

Summary

AZD6482 is a new drug substance aiming to prevent blood clots which may arise in atherosclerotic blood vessels and cause myocardial infarction or stroke. This is the first study with AZD6482 in humans. The primary aim for this study is to evaluate the safety and tolerability of AZD6482 in healthy human volunteers. How the substance is metabolised and eliminated from the body will also be studied. This will be done by comparing the effect of single ascending doses of AZD6482 to placebo (inactive substance).

Timeline

Start
2008-01
Primary completion
2008-05
Completion
2008-05

Drugs

EvaluationDrugModalityDoseRoute
Subject AZD6482 Small molecule Intravenous

Indications

No indication recorded.