Randomized, Double-Blind, Placebo-Controlled, Phase 2 Study In Subjects With Osteoarthritic Pain Of The Knee

Summary

To evaluate the efficacy, safety, tolerability, pharmacodynamics, and pharmacokinetics in patients with osteoarthritic pain of the knee. The most painful knee joint will be identified as the index joint at screening, and this joint will be used for all pain assessments throughout the study.

Timeline

Start

2008-08-05

Primary completion

2008-11-27

Completion

2008-11-27

Outcome

Missed primary endpoint

registry analysis (superiority test); PF-04136309 vs Placebo; p = 0.39; Least Square (LS) Mean Difference -0.49 (80% CI -1.23 to 0.24); Mixed Models Analysis NCT00689273 ↗

Drugs

Indications