Palatability of Oral Rehydration Solutions

Phase 3 Completed 66 enrolled The Hospital for Sick Children

RandomizedCrossoverQuadruple-blindOther

Summary

The primary objective of this study is to compare the mean taste scores for three fruit flavored oral rehydration solutions in children aged 5-10 years old. The secondary objective is to compare the proportions of children who indicate a taste preference for one of the solutions.

Timeline

Start: 2008-05
Primary completion: 2008-08
Completion: 2008-08

Outcome

Met primary endpoint

paper Sucralose-sweetened oral rehydration solutions (Pedialyte and Pediatric Electrolyte) were significantly more palatable than was a comparable rice-based solution (Enfalyte). PMID 20679159 ↗

Publications

Freedman SB, Cho D, Boutis K, Stephens D, Schuh S. Assessing the palatability of oral rehydration solutions in school-aged children: a randomized crossover trial. Arch Pediatr Adolesc Med. 2010 Aug;164(8):696-702. doi: 10.1001/archpediatrics.2010.129.

Drugs

Evaluation	Drug	Modality	Dose	Route
Comparator	Enfalyte	Unknown	250 ml	Oral
Subject	Pedialyte	Unknown	250 ml	Oral
Subject	Pediatric Electrolyte	Unknown	250 ml	Oral