drugset / Trial / NCT00692705

Positron Emission Tomography (PET) Study With [11C]AZD2995 and [11C]AZD2184, Candidate PET Ligands for β Amyloid

NCT00692705 ↗

Phase 1 Completed 13 enrolled AstraZeneca
Non-randomizedParallel-groupOpen-labelBasic science

Summary

The study is carried out in order to investigate if \[11C\]AZD2995, compared to \[11C\]AZD2184, is a more suitable PET ligand for in vivo imaging of β amyloid depositions in the human brain. In the study the two PET ligands will be examined in both healthy volunteers and patients with Alzheimer's Disease.

Timeline

Start
2008-01
Primary completion
2008-12
Completion
2008-12

Drugs

EvaluationDrugModalityDoseRoute
Subject AZD2184 Diagnostic / imaging agent — Intravenous
Subject AZD2995 Diagnostic / imaging agent — Intravenous

Indications