drugset / Trial / NCT00692926

Unrelated Umbilical Cord Blood Transplantation Augmented With ALDHbr Umbilical Cord Blood Cells

NCT00692926 ↗

Phase 1 Completed 37 enrolled Joanne Kurtzberg, MD Aldagen · collab
Non-randomizedSingle-groupOpen-labelTreatment

Summary

The main purpose of this investigational (not approved by the FDA) Phase I research is to test whether transplantation of umbilical cord blood cells can be safely supplemented with a transfusion of a portion of these cells that have been sorted (collected from a special machine called a cell sorter) and then either infused a few hours after the standard transplant or for some patients grown in a special system in the laboratory prior to the transplant, designed to increase the number of stem cells transplanted. This system is currently in the early phases of testing.

Timeline

Start
2005-10
Primary completion
2012-07
Completion
2012-07

Drugs

EvaluationDrugModalityDoseRoute
Subject ALDHbr Umbilical Cord Blood Cells Cell therapy — —