drugset / Trial / NCT00693342

Vaccine Therapy and OPT-821 or OPT-821 Alone in Treating Patients With Ovarian Epithelial Cancer, Fallopian Tube Cancer, or Primary Peritoneal Cancer in Complete Remission

NCT00693342 ↗

RandomizedTreatment

Summary

RATIONALE: Vaccines made from tumor antigens may help the body build an effective immune response to kill tumor cells. Biological therapies, such as OPT-821, may stimulate the immune system in different ways and stop tumor cells from growing. Giving vaccine therapy together with OPT-821 may kill more tumor cells. It is not yet known whether giving vaccine therapy together with OPT-821 is more effective than OPT-821 alone in treating ovarian epithelial cancer, fallopian tube cancer, or primary peritoneal cancer. PURPOSE: This randomized phase III trial is studying vaccine therapy and OPT-821 to see how well they work compared with OPT-821 alone in treating patients with ovarian epithelial cancer, fallopian tube cancer, or primary peritoneal cancer in complete remission.

Timeline

Start
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Primary completion
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Completion
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Outcome

Outcome not reported

Stopped (Enrollment): “Never opened to accrual, a GOG working number, not developed into a clinical trial.”

Drugs

EvaluationDrugModalityDoseRoute
Subject OBI-821 Other / unclassified — Subcutaneous
Subject polyvalent antigen-KLH conjugate vaccine Vaccine — Subcutaneous