drugset / Trial / NCT00693758
Assessment of Oxygen Changes in the Heart With Cardio-vascular Magnetic Resonance Imaging
Non-randomizedSingle-groupOpen-labelDiagnostic
Summary
The ability of a new SSFP-based BOLD MRI sequence to assess myocardial oxygenation changes in response to coronary flow changes induced by adenosine and increased CO2-partial pressure will be examined in healthy volunteers and patients with suspected coronary artery disease. Also the susceptibility of a new SSFP-based BOLD sensitive MRI sequence to changes in arterial oxygenation will be examined. This will help understand the physiologic basis of oxygen sensitive imaging of the heart.
Timeline
- Start
- 2006-01
- Primary completion
- 2011-09
- Completion
- 2011-09
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Adenosine | Small molecule | 140 ug/kg | Intravenous |