drugset / Trial / NCT00693758

Assessment of Oxygen Changes in the Heart With Cardio-vascular Magnetic Resonance Imaging

NCT00693758

Phase 0 Completed 100 enrolled University of Calgary
Non-randomizedSingle-groupOpen-labelDiagnostic

Summary

The ability of a new SSFP-based BOLD MRI sequence to assess myocardial oxygenation changes in response to coronary flow changes induced by adenosine and increased CO2-partial pressure will be examined in healthy volunteers and patients with suspected coronary artery disease. Also the susceptibility of a new SSFP-based BOLD sensitive MRI sequence to changes in arterial oxygenation will be examined. This will help understand the physiologic basis of oxygen sensitive imaging of the heart.

Timeline

Start
2006-01
Primary completion
2011-09
Completion
2011-09

Drugs

EvaluationDrugModalityDoseRoute
Subject Adenosine Small molecule 140 ug/kg Intravenous

Indications