drugset / Trial / NCT00694343
Efficacy of Voluven® for the Prevention of Hypotension During Spinal Anesthesia for Cesarean Section
RandomizedParallel-groupQuadruple-blindPrevention
Summary
The aim of the study is to evaluate the efficacy of Voluven® in the prevention of maternal hypotension in women undergoing spinal anesthesia for cesarean section
Timeline
- Start
- 2008-06
- Primary completion
- 2009-12
- Completion
- 2010-06
Publications
- Chooi C, Cox JJ, Lumb RS, Middleton P, Chemali M, Emmett RS, Simmons SW, Cyna AM. Techniques for preventing hypotension during spinal anaesthesia for caesarean section. Cochrane Database Syst Rev. 2020 Jul 1;7(7):CD002251. doi: 10.1002/14651858.CD002251.pub4.
- Mercier FJ, Diemunsch P, Ducloy-Bouthors AS, Mignon A, Fischler M, Malinovsky JM, Bolandard F, Aya AG, Raucoules-Aime M, Chassard D, Keita H, Rigouzzo A, Le Gouez A; CAESAR Working Group. 6% Hydroxyethyl starch (130/0.4) vs Ringer's lactate preloading before spinal anaesthesia for Caesarean delivery: the randomized, double-blind, multicentre CAESAR trial. Br J Anaesth. 2014 Sep;113(3):459-67. doi: 10.1093/bja/aeu103. Epub 2014 Jun 26.
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Ringer's Lactate solution | Unknown | 500 ml | Intravenous |
| Comparator | Ringer's Lactate solution | Unknown | 1000 ml | Intravenous |
| Subject | Volulyte | Other / unclassified | 500 ml | Intravenous |