Evalution of Immunogenicity, Safety and Booster Response of a Rabies Vaccine Administered Concomitantly With Japanese Encephalitis Vaccine in Toddlers

Phase 2 Completed 200 enrolled Novartis Novartis Vaccines · collab

RandomizedParallel-groupOpen-labelPrevention

Summary

This study evaluated the safety and immunogenicity of rabies vaccine and Japanese encephalitis vaccine in toddlers. All children developed adequate immune responses. Rabies vaccination with PCECV did not interfere with the antibody response to Japanese encephalitis vaccine. The rabies vaccine PCECV and Japanese encephalitis vaccine are safe and immunogenic when administered concomitantly to toddlers.

Timeline

Start: 2002-08
Primary completion: 2004-08
Completion: 2004-09

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	IC51	Vaccine	0.25 ml	Subcutaneous
Subject	Rabies vaccine	Vaccine	0.1 ml	Intramuscular
Subject	Rabies vaccine	Vaccine	0.5 ml	Intramuscular
Subject	Rabies vaccine	Vaccine	1 ml	Intramuscular

Evalution of Immunogenicity, Safety and Booster Response of a Rabies Vaccine Administered Concomitantly With Japanese Encephalitis Vaccine in Toddlers

Summary

Timeline

Drugs

Indications