drugset / Trial / NCT00694837
Study With Nelfinavir and Combined Radiochemotherapy for Glioblastoma
Phase 1
Completed
6 enrolled
Maastricht Radiation Oncology
Maastricht University Medical Center · collab
NaSingle-groupOpen-labelTreatment
Summary
The objectives of the trial are: To assess safety, tolerability and activity of nelfinavir given neo-adjuvant and concomitant to chemoradiotherapy with temozolomide in patients with a newly diagnosed glioblastoma multiforme. To describe the possible effect of nelfinavir on functional imaging To describe the activity of nelfinavir in vivo on blocking the AKT pathway.
Timeline
- Start
- 2009-03
- Primary completion
- 2013-01
- Completion
- 2013-01
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Nelfinavir | Other / unclassified | 1000 mg | — |
| Subject | Nelfinavir | Other / unclassified | 1250 mg | — |