drugset / Trial / NCT00697229

Immunogenicity & Reactogenicity of HBV-MPL Vaccine and Engerix™-B in Healthy Adults Following 2 Different Schedules

NCT00697229

Phase 2 Completed 99 enrolled GlaxoSmithKline
RandomizedParallel-groupDouble-blindPrevention

Summary

The purpose of this study is to evaluate the safety, immunogenicity and reactogenicity of MPL-adjuvanted recombinant hepatitis B vaccine in comparison with those of Engerix™-B in healthy adult volunteers following two different schedules: 0, 2 months and 0, 6 months

Timeline

Start
1992-09
Primary completion
1996-05
Completion
1998-12

Drugs

EvaluationDrugModalityDoseRoute
Subject Engerix-B Vaccine Intramuscular
Subject HBV-MPL vaccine Vaccine Intramuscular