drugset / Trial / NCT00698555

Comparing Immunogenicity and Safety of Different Formulations of HBV-MPL Vaccine With Engerix™-B in Adults Aged 18-40 y

NCT00698555

Phase 2 Completed 163 enrolled GlaxoSmithKline
RandomizedParallel-groupOpen-labelPrevention

Summary

This study will evaluate the immunogenicity and safety of different formulations of the candidate HBV-MPL vaccine administered according to a 2-dose schedule and compare it to that of Engerix™-B administered according to a 3-dose schedule in order to determine the optimal dose of each component of the candidate HBV-MPL vaccine when administered at 0 and 6 months

Timeline

Start
1997-03
Primary completion
1998-05
Completion

Drugs

EvaluationDrugModalityDoseRoute
Comparator Engerix-B Vaccine Intramuscular
Subject HBV-MPL vaccine Vaccine Intramuscular