Alpha-blocker Plus Diuretic Combination Therapy as Second-line Treatment for Nocturia in Men

Completed 72 enrolled Seoul National University Hospital

NaSingle-groupOpen-labelTreatment

Summary

The aim of the present study was to determine whether the combined administration of a diuretic agent, hydrochlorothiazide, at night would improve the frequency of nocturia unresponsive to alpha-blocker monotherapy in men with LUTS.

Timeline

Start: 2008-05
Primary completion: 2008-06
Completion: 2008-06

Publications

Results Cho MC, Ku JH, Paick JS. Alpha-blocker plus diuretic combination therapy as second-line treatment for nocturia in men with LUTS: a pilot study. Urology. 2009 Mar;73(3):549-53; discussion 554-5. doi: 10.1016/j.urology.2008.08.517. Epub 2008 Dec 18.

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	Hydrochlorothiazide	Unknown	25 mg	—
Background	Terazosin	Small molecule	4 mg	—

Indications

No indication recorded.