drugset / Trial / NCT00701220

Statin Therapy for Ischemic and Nonischemic Cardiomyopathy

NCT00701220 ↗

Phase 4 Completed 9 enrolled Philip Binkley Pfizer · collab
Non-randomizedParallel-groupOpen-labelTreatment

Summary

The purpose of this study is to see if taking a cholesterol lowering drug Lipitor (Atorvastatin Calcium)will increase the number of endothelial progenitor cells (EPC's) circulating in the blood of heart failure patients taking this cholesterol-lowering drug, and if this will also show an improvement in the damaged areas of the patient's hearts as documented by MRI scans.

Timeline

Start
2007-04
Primary completion
2010-12
Completion
2010-12

Publications

  • Background Abstract 10678: Increase in the Number of Circulating Primordial Cells is Associated With Improved Left Ventricular Function in Dilated Cardiomyopathy Nkechinyere N Ijioma, Philip F Binkley, and Amanda Lesinski Originally published27 Mar 2018Circulation. 2013;128:A10678

Drugs

EvaluationDrugModalityDoseRoute
Comparator Atorvastatin Small molecule 40 mg —