drugset / Trial / NCT00702117
Ajmaline Utilization in the Diagnosis and Treatment of Cardiac Arrhythmias
RandomizedParallel-groupOpen-labelTreatment
Summary
The study evaluates 3 different populations: It is an open, randomized, parallel-group study comparing the effectiveness of intravenous (iv) ajmaline with currently used antiarrhythmic drugs in the acute treatment of : 1. recent-onset atrial fibrillation versus iv flecainide 2. sustained monomorphous ventricular tachycardia versus iv procainamide The study also evaluates in an open, randomized, crossover study, the use of iv ajmaline versus iv flecainide in the diagnosis of Brugada syndrome
Timeline
- Start
- 2008-06
- Primary completion
- 2010-01
- Completion
- 2010-01
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Ajmaline | Small molecule | 1 mg/kg | Intravenous |
| Comparator | Procainamide | Small molecule | 10 mg/kg | Intravenous |
| Comparator | flecainide | Small molecule | 2 mg/kg | Intravenous |