Tolerance of Increased Infusion Rates of Intravenous Fat Emulsions in Very Low Birth Weight Infants

Summary

This study was completed in October 2006. No further participates are being recruited.

Timeline

Start

2005-07

Primary completion

2006-10

Completion

2007-04

Outcome

Results reported · no primary-endpoint met/missed verdict (typical of a dose-finding / safety study)

paper The primary clinical outcome was serum triglyceride levels; secondary outcomes also were monitored. PMID 18829797 ↗

paper Triglyceride levels for infants in the experimental group remained significantly higher for the first 5 days of life. PMID 18829797 ↗

Publications

• Drenckpohl D, McConnell C, Gaffney S, Niehaus M, Macwan KS. Randomized trial of very low birth weight infants receiving higher rates of infusion of intravenous fat emulsions during the first week of life. Pediatrics. 2008 Oct;122(4):743-51. doi: 10.1542/peds.2007-2282.

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	INTRALIPIDS	Unknown	—	Intravenous

Indications

No indication recorded.