drugset / Trial / NCT00703586
Study of the Antiviral and Immunological Effects of Intensification of Suppressive Antiretroviral Therapy With Maraviroc
Phase 1
Completed
8 enrolled
Rockefeller University
Aaron Diamond AIDS Research Center · collabPfizer · collab
RandomizedCrossoverOpen-labelTreatment
Summary
Hypothesis: Intensification of current ARV regimens with maraviroc will result in more complete suppression of viral replication, particularly in the gastrointestinal mucosa with resultant reduction in markers of immune activation and improved GI immune reconstitution.
Timeline
- Start
- 2007-09
- Primary completion
- 2011-05
- Completion
- 2011-05
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Maraviroc | Other / unclassified | 150 mg | Oral |
| Subject | Maraviroc | Other / unclassified | 600 mg | Oral |